The flight marks the beginning of a flight test programme involving six aircraft, culminating in the aircraft's first delivery scheduled for fourth quarter 2010.
Powered by two Rolls-Royce Trent 1000 engines, the first Boeing 787 Dreamliner will be joined in the flight test programme by five other 787s, including two that will be powered by General Electric GEnx engines.
55 customers around the world have ordered 840 787s.
Further information
This first flight comes at the end of a series of delays to the Dreamliner programme. For an overview of the project and the problems it has encountered see our feature: Boeing's 787: trials, tribulations, and restoring the dream.